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Regulatory Role of Supramolecular Alcohol Dehydrogenase and Lactate Dehydrogenase Complex in Cell Mitochondria
Authors:Zimin Yu V  Solovyova A G
Affiliation:(1) Department of Botany, Graduate School of Science, Kyoto University, Kitashirakawa, Sakyo-ku, Kyoto 606-8502, Japan
Abstract:The existence of a supramolecular alcohol dehydrogenase–lactate dehydrogenase complex was demonstrated. Enzyme activities were evaluated in a preparation of mitochondrial membranes from mouse liver. The role of the enzyme complex (alcohol dehydrogenase–lactate dehydrogenase) in the regulation of pyruvate and acetaldehyde metabolism in the cell was studied.
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