| 诺和锐30和诺和灵30R治疗2型糖尿病疗效及剂量比较 |
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| 引用本文： | 丁丽萍,李华颖. 诺和锐30和诺和灵30R治疗2型糖尿病疗效及剂量比较[J]. 中国现代医药杂志, 2008, 10(10) |
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| 作者姓名： | 丁丽萍 李华颖 |
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| 作者单位： | 内蒙古呼伦贝尔市人民医院内分泌科,021008 |
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| 摘 要： | 目的观察CSII强化治疗后的2型精尿病患者改用诺和锐30和诺和灵30R的疗效及剂量比较。方法120例经CSII强化治疗达标（FBG〈7mmol／L，2hBG〈10mmol／L）的2型糖尿病患者随机分为A组：诺和锐30组（60例），B组：诺和灵30R组【对照组，60例）。观察患者日胰岛素总量、血糖控制情况、体质量及低血糖发生率。结果两组患者治疗12周后FBG、PBG2h均调整至正常范围，体质量变化差异无统计学意义。未出现皮疹、发热、瘙痒、肝功损害情况。但A组24小时血糖控制更稳定，日胰岛素用量A组明显少于B组，两组差异有统计学意义，P〈0.01。低血糖和其他不良事件：诺和锐30组低血糖发生率明显少于诺和灵30R组，两组差异有统计学意义，P〈0.01。两组均无严重低血糖事什记录。结论诺和锐30较诺和灵30R能更有效怏速降低血糖，有良好的安全件及依从性。且诺和锐30组剂量明显少于诺和灵30R组。
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| 关 键 词： | 人胰岛素 胰岛素类似物 2型糖尿病 |
Comparison of the curative effect and dosage between NovoMix30 and Novolin 30R treating patients with Type 2 Diabetes after the intensification therapy with insulin pump |
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| Ding Liping,Li Huaying. Comparison of the curative effect and dosage between NovoMix30 and Novolin 30R treating patients with Type 2 Diabetes after the intensification therapy with insulin pump[J]. Modern Medicine Journal of China, 2008, 10(10) |
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| Authors: | Ding Liping Li Huaying |
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| Affiliation: | Ding Liping,Li Huaying.Department of Endocrinology of Hulun Beier City People's Hospital in Inner Mongolia Postcode,Neimenggu 021008 |
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| Abstract: | Objective To study the difference of curative effect and dosage between NovoMix 30 and novolin 30R treating the patients with type 2 diabetes undergoing the intensification therapy with insulin pump. Methods 120 patients with type 2 diabetes undergoing intensification therapy with CSII , whose blood glucose concentration had been up to the standard (FBG<7mmol/L, 2hBG<10mmol/L ), were randomly divided into group NovoMix 30 (60 patients ) ( group A ) and group Novolin 30R (60 patients ) ( group B ).The daily ... |
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| Keywords: | Human Insulin Insulin analogue Type 2 diabetes mellitus |
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