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红景天甙、酮对大鼠离体工作心脏心功能的影响
作者单位:Department of Physiology,Central Laboratory of Physiofogy
摘    要:作者用红景天的提取物甙、酮灌流Wistar大鼠离体工作心脏,观察主动脉压、左室最高压、左室舒末压、室内压最大上升速率、室内压最大下降速率、主动脉流量、冠脉流量及心输出量、每搏输出量、心率等10项心功能指标。红景天甙和酮均可以使反映心肌收缩性的各项指标显著降低,二者间作用无明显差别。结果表明红景天甙和酮均可以减弱离体工作心肌的收缩性能。

关 键 词:红景天甙  红景天酮  心肌收缩性能  离体工作心脏

Effect of rhodiola saponin and rhodiola ketone on cardiac function of isolated working heart in rats
Authors:Fang Jiazhi  Sun Xilloxia  Zhang Xiaoyan  
Abstract:Rhodiola saponin and rhtaliola ketone were respectively infused into isolated workingheart in rats. The below indicators of cardiac function,including the aortic pressure,LVST,LVEDP,+dp/dtmax,一dp/dt max aortic blood flow,coronary blood flow,cardiac output,stroke volume and heartrate,were measured.Both the rhodiola saponin and rhodiola ketone could obviously decline the indica- tors that indicate the function of myocardial contractility and the actions had not marked difference. This data suggest that both rhodiola saponin and rhodiola ketone could reduce niyocardial contractilityof isolated wcrking heart.
Keywords:rhodiola saponin  rhodiola ketone  rnyocardial contractility  isolated working heart  
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