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乳腺癌患者围手术期凝血功能的变化
引用本文:杨晓民,任宏,邓智平,宋张骏,李逢生,马冬梅.乳腺癌患者围手术期凝血功能的变化[J].陕西肿瘤医学,2010,18(4):695-696.
作者姓名:杨晓民  任宏  邓智平  宋张骏  李逢生  马冬梅
作者单位:[1]西安交通大学医学院第一附属医院,陕西西安710061 [2]陕西省肿瘤医院,陕西西安710061
摘    要:目的:研究乳腺癌术后患者血液凝血功能的变化。方法:随机选出50名(ASAⅠ-Ⅱ级)乳腺癌患者,分别测定手术前后凝血系列(FIB,TT,PT,APTT,ALT)。结果:乳腺癌患者术后FIB明显高于术前(P〈0.05),APTT明显低于术前(P〈0.05),PLT较术前增高(P〈0.05)。结论:乳腺癌术后患者血液呈高凝状态,因而术后存在深部静脉血栓和肺栓塞的危险,及时预防治疗具有重要临床意义。

关 键 词:乳腺癌  高凝状态  血栓

Investigation of perioperative hemostatic alterations in patients with breast cancer
YANG Xiao-min,REN-Hong,DENG Zhi-ping,SONG Zhang-jun,LI Feng-sheng,MA Dong-mei.Investigation of perioperative hemostatic alterations in patients with breast cancer[J].Shaanxi Oncology Medicine,2010,18(4):695-696.
Authors:YANG Xiao-min  REN-Hong  DENG Zhi-ping  SONG Zhang-jun  LI Feng-sheng  MA Dong-mei
Institution:1.The First Affiliated Hospital,Medicine School,Xi'an Jiaotong University,Xi'an 710061,China;2.Department of Gynecology Oncology,Shaanxi Province Tumor Hospital,Xi'an 710061,China.)
Abstract:Objective:To invest the change of perioperative hemostatic alterations in patients with breast cancer.Methods: To test the serial of perioperative hemostatic alterations(FIB,TT,PT,APTT,PLT)in 50 breast cancer patients(ASAⅠ-Ⅱgrade).Results: FIB and PLT of the patiets with breast cancer were higher preoperatively than that postoperatively(P〈0.05),APTT obviously decreased postoperatively(P〈0.05).Conclusion: Patients with breast cancer in postoperative stage were in hypercoagulabale state(HCS),consequently,deep vein thrombosis(dvt) and lung embolism may develop,prevention and therapy in time are important.
Keywords:breast cancer  hypercoagulabale state  thrombus
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