| 均匀设计法优化超高压提取虎杖中虎杖苷和白藜芦醇 |
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| 引用本文： | 廖国平,贺帅,张忠义.均匀设计法优化超高压提取虎杖中虎杖苷和白藜芦醇[J].中国中药杂志,2010,35(24):3282-3286. |
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| 作者姓名： | 廖国平 贺帅 张忠义 |
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| 作者单位： | 南方医科大学珠江医院药剂科,广东,广州,510282 |
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| 基金项目： | 广东省自然科学基金项目(8151051501000054) |
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| 摘 要： | 目的:应用超高压技术提取虎杖中虎杖苷和白藜芦醇,并结合均匀设计试验优选最佳工艺。方法:在单因素试验的基础上,采用均匀设计试验U9(96)对虎杖中虎杖苷和白藜芦醇超高压提取的工艺参数进行优选,并与回流提取、超声提取和微波提取进行比较。结果:超高压提取虎杖苷及白藜芦醇的最佳工艺条件为溶剂55%乙醇,压力170 MPa,液固比30 mL.g-1,提取时间120 s;此提取条件下虎杖苷及白藜芦醇的提取率分别为14.29,2.53 mg.g-1;虎杖苷提取率分别高出回流提取46.1%,超声提取6.4%和微波提取28.5%,白藜芦醇提取率分别高出回流提取67.5%,超声提取29.7%和微波提取24.6%。结论:超高压提取作为一种新兴的中药提取技术,具有提取率高、提取温度低、耗时短、能耗少等优点,为虎杖中虎杖苷及白藜芦醇的提取提供了一个全新的方法。
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| 关 键 词： | 超高压提取 均匀设计法 虎杖苷 白藜芦醇 |
| 收稿时间： | 2010/6/15 0:00:00 |
Optimization of ultrahigh pressure extraction for polydatin and resveratrol from Polygonum cuspidatum by using uniform design |
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| LIAO Guoping,HE Shuai and ZHANG Zhongyi.Optimization of ultrahigh pressure extraction for polydatin and resveratrol from Polygonum cuspidatum by using uniform design[J].China Journal of Chinese Materia Medica,2010,35(24):3282-3286. |
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| Authors: | LIAO Guoping HE Shuai and ZHANG Zhongyi |
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| Institution: | Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China;Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China;Department of Pharmacy, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China |
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| Abstract: | |
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| Keywords: | ultrahigh pressure extraction uniform design polydatin resveratrol |
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