| 天然产物5,7-二甲氧基木犀草素的合成 |
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| 引用本文： | 吴龙火,张剑.天然产物5,7-二甲氧基木犀草素的合成[J].赣南医学院学报,2012,32(4):495-496. |
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| 作者姓名： | 吴龙火 张剑 |
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| 作者单位： | 赣南医学院药学院,江西赣州,341000 |
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| 基金项目： | 江西省卫生厅课题,江西省教育厅课题 |
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| 摘 要： | 5,7-二甲氧基木犀草素是中药枳椇中一种黄酮类主要化合物之一。本文以芦丁为原料,经水解还原得到木犀草素,再经羟基保护、醚化及脱保护基等反应合成了5,7-二甲氧基木犀草素,总收率为7.9%。其结构经1HNMR和13C NMR表征。
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| 关 键 词： | 枳椇 芦丁 木犀草素 5 7-二甲氧基木犀草素 |
Synthesis of natural flavone: 5-methoxy-luteolin |
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| WU Long-huo
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ZHANG Jian.Synthesis of natural flavone: 5-methoxy-luteolin[J].Journal of Gannan Medical College,2012,32(4):495-496. |
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| Authors: | WU Long-huo ZHANG Jian |
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| Institution: | (Pharmacy College of Gannan Medical University,Ganzhou,Jiangxi,341000) |
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| Abstract: | 5,7-dimethoxy-luteolin is one of main flavones in Traditional Chinese Medicine Hovenia dulcis Thunb.Luteolin was obtained from the hydrolysis of rutin.5,7-dimethoxy-luteolin in total yield of 7.9% was synthesized by reaction of protection of hydroxyl group,etherification,and deprotection.The structures were confirmed by 1H NMR and 13C NMR. |
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| Keywords: | Hovenia dulcis Thunb rutin luteolin 5 7-dimethoxy-luteolin |
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