| 复方苦参注射液对125I粒子植入治疗的消化道恶性肿瘤患者免疫功能的影响 |
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| 引用本文： | 隋爱霞,李冬军,沈永青,王娟,李庆霞,张明.复方苦参注射液对125I粒子植入治疗的消化道恶性肿瘤患者免疫功能的影响[J].河北中医,2012,34(5):726-728. |
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| 作者姓名： | 隋爱霞 李冬军 沈永青 王娟 李庆霞 张明 |
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| 作者单位： | 隋爱霞 (河北省人民医院肿瘤一科,河北石家庄,050051) ； 李冬军 (河北省石家庄市第一医院烧伤科,河北石家庄,050016) ； 沈永青 (河北医科大学西山校区内科教研室,河北石家庄,050200) ； 王娟 (河北省人民医院肿瘤一科,河北石家庄,050051) ； 李庆霞 (河北省人民医院肿瘤一科,河北石家庄,050051) ； 张明 (河北省人民医院肿瘤一科,河北石家庄,050051) ； |
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| 基金项目： | 河北省2008年医学科学研究重点课题计划 |
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| 摘 要： | 目的探讨复方苦参注射液对实施放射性125I粒子植入治疗的消化道恶性肿瘤患者免疫功能的影响。方法将44例消化道恶性肿瘤患者随机分为2组。2组均予放射性125I粒子植入治疗,治疗组加用复方苦参注射液治疗,1个月后测定患者T淋巴细胞亚群CD4+、CD8+及免疫球蛋白(Ig)G、IgA、IgM变化。结果治疗组治疗前后CD4+、CD8+、CD4+/CD8+及IgG、IgA、IgM水平比较差异有统计学意义(P<0.05),对照组治疗前后比较差异无统计学意义(P>0.05);2组治疗后CD4+、CD8+、CD4+/CD8+及IgG、IgA、IgM水平比较差异有统计学意义(P<0.05)。结论复方苦参注射液能够增强应用放射性125I粒子植入治疗的消化道恶性肿瘤患者免疫功能。
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| 关 键 词： | 消化系统肿瘤 碘放射性同位素 免疫 苦参 中药疗法 |
Investigation of compound Kushen injection on the immune function of patients with gastrointestinal cancer treated by 125^I interstitial brachytherapy |
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| Institution: | SUI Aixia ,LI Dongjun,SHEN Yongqing,et al.(Cancer Division One,Hebei Provincial People＇s Hospital, Hebei , Shijiazhuang 050051) |
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| Abstract: | Abstract】 Objective To investigate effect of compound Kushen injection on the immune function of patients with gastrointestinal cancer treated by 125I interstitial brachytherapy.Methods 44 cases of gastrointestinal cancer were randomly divided into two groups.Patients in two groups were treated by 125I interstitial brachytherapy.And treatment group received compound Kushen injection.Lymphocyte subsets of CD4^＋ and CD8^＋ and IgG,IgA,and IgM levels in two groups were detected after a month.Results There was statistical significance between before and after treatment on CD4^＋,CD8^＋ and CD4^＋/CD8^＋ and IgG,IgA,and IgM levels in treatment group（P〈0.05）.But there was no statistical significance between between before and after treatment in control group（P〉0.05）.There was statistical significance between two groups on CD4^＋,CD8^＋ and CD4^＋/CD8^＋ and IgG,IgA,and IgM levels after treatment（P〈0.05）.Conclusion Compound Kushen injection can enhance the immune function of patients with gastrointestinal cancer treated by 125I interstitial brachytherapy. |
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| Keywords: | Digestive system neoplasms Iodine radioisotopes Immune Sophora flavescens TraditionalChinese Medicine therapy |
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