后扩张治疗对老年冠状动脉钙化病变PCI术的疗效和安全性研究

目的观察常规后扩张治疗对老年冠状动脉钙化病变经皮冠状动脉介入治疗（PCI）的疗效和安全性。方法选择血管造影成功的老年钙化病变冠心病患者124例，随机分为后扩张组（治疗组，62例）和常规置入组（对照组，62例）。观察两组术中并发症发生率，住院期间及1年后支架内血栓、再狭窄和主要不良心脏事件（MACE）发生率。结果后扩张组和常规置入组患者PCI中并发症发生率比较差异无统计学意义（6．5％比4．8％，P〉0．05）。1年后的随访结果显示，后扩张组的MACE事件发生率较对照组降低（4．8％比12．9％，P〈0．05）；支架内血栓和支架内再狭窄发生率较常规置人组均明显减少（1．6％比4．8％，4．4％比14．3％），差异有统计学意义（P〈0．05）。结论在老年冠状动脉钙化病变PCI中常规后扩张治疗安全、有效，能减少术后不良心脏事件从而改善预后。

Efficacy and safety of routine post-dilatation approoach in the treatment of coronary calcification lesions during percutaneous coronary intervention

Objective To observe the clinical therapeutic effect and security of adjunctive balloon postdilatation applying to percutaneous coronary intervention for elderly patients with coronary artery calcification lesion. Methods 124 elderly patients with coronary artery calcification lesion and successful angiograph in our hospital were randomly divided into the post-dilatation deployment group （n=62） and the control group （n=62）. The complications of intraoperative and stent thrombosis, stent restenosis and major adverse cardiac events （MACE） within hospitalization and one year were observed. Results Intraoperative complications were similar between the two groups （6.5% vs 4.8%, P〉0.05）. Stent thrombosis, stent restenosis, major adverse cardiac events were significantly lower in post-dilatation deployment group than in control group at 1 year （1.6% vs 4.8%, 4.4% vs 14.3%, 4.8% vs 12.9%, all P〈0.05）. Conclusion Routine post-dilatation approach is safe and effective for elderly patients with coronary artery calcification lesion undergoing PCI. It can decrease major adverse cardiac events and