Abstract: | Investigations of mammary glands of 241 patients of 50-70 years of age or older suffering from carcinoma and having been is menopause for 10 years or more established that the main histological form of carcinoma was infiltrating carcinoma of glandular, solid, solid-scirrhous structure of various degrees of malignancy (I, II, III) (81.3%), irrespective of the age and duration of menopause. The main forms of carcinoma were observed in occasional cases, most frequently it was lobular invasive carcinoma (8.3%). In 65% of the patients carcinoma was detected in the presence of involutive processes and changes corresponding to nonproliferating mastopathy. In one-third of the patient carcinomas developed in the presence of proliferative processes, half of these patients showing transition from proliferation of the epithelium of ducts and lobules to cancer in situ and its invasion into the surrounding tissues of mammary glands. |