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针刺内关穴与非穴的fMRI脑功能成像研究
引用本文:张贵锋,赖新生,黄泳,吴俊贤,曾统军,李赣龙,邹燕齐.针刺内关穴与非穴的fMRI脑功能成像研究[J].辽宁中医杂志,2009(5):810-812.
作者姓名:张贵锋  赖新生  黄泳  吴俊贤  曾统军  李赣龙  邹燕齐
作者单位:南方医科大学;广州中医药大学;
基金项目:国家重点基础研究发展计划(973计划)(2006CB504505);;国家自然科学基金重大研究计划课题(90709027)
摘    要:目的:观察针刺健康志愿者右侧内关穴和非穴时不同脑区的激活情况,探讨针刺穴位对脑中枢的激活效应。方法:将14例健康志愿者随机分为内关穴组和非穴组,分别针刺右侧内关穴和非穴;同时,运用GE公司1.5T超导核磁共振系统完成脑部fMRI扫描,获得局部脑组织激活与否的试验数据,采用感兴趣区(ROI)法进行处理和分析。结果:针刺内关穴和非穴,对双侧顶叶、额叶、枕叶、颞叶、基底节区、扣带回、小脑、脑桥、脑岛等多个脑区分别有不同程度的激活;从激活几率、激活数量和激活强度上看,针刺右侧内关穴以激活左侧顶叶、额叶、颞叶、枕叶为主,并且特异性激活左侧海马和双侧桥脑;尽管在脑区的激活上,有上述趋势,但是在统计学上无显著性意义(P>0.05)。结论:针刺内关穴和非穴激活的脑区有相对的差异性,针刺外周穴位能特异性的激活脑中枢。

关 键 词:内关穴  非穴  fMRI  脑功能成像  中枢效应

An fMRI cerebral functional imaging study on needling in Neiguan(PC6)vs a sham point
ZHANG Gui-feng,LAI Xin-sheng,HUANG Yong,WU Jun-xian,ZENG Tong-jun,LI Gan-long,ZOU Yan-qi.An fMRI cerebral functional imaging study on needling in Neiguan(PC6)vs a sham point[J].Liaoning Journal of Traditional Chinese Medicine,2009(5):810-812.
Authors:ZHANG Gui-feng  LAI Xin-sheng  HUANG Yong  WU Jun-xian  ZENG Tong-jun  LI Gan-long  ZOU Yan-qi
Institution:1.School of Traditional Chinese Medicine;Southern Medical University;Guangzhou 510515;China;2.Acupunture and Massage College;Guangzhou Traditional Chinese Medicine University;Guangzhou 510407;China
Abstract:Objective:To observe cerebral activation of healthy volunteers received needling Neiguan vs a sham point in the right hands,and to explore activation effect of acupoint needling on the central brain.Methods:Fourteen healthy volunteers were randomly divided into Neiguan true group and sham point group,and received needling in PC6 and the sham point respectfully.Super nuclear magnetic resonance(1.5T,from GE Company)was used to scan the brain and the obtained experimental data in the regional brain were proces...
Keywords:Neiguan (PC6)  sham point  fMRI  cerebral functional imaging
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