超声检查及血清CA125测定诊断子宫腺肌病的评价

目的探讨超声检查及血清癌抗原125(CA125)测定对子宫腺肌病的诊断价值.方法通过对120例疑为子宫腺肌病或子宫肌瘤患者,行术前腹部B超和血清CA125测定;术后切下组织送病理学检查确诊并与之对照.结果经术后病理学证实子宫腺肌病组术前血清CA125检测敏感度73.8%, 特异度73.5%; B超诊断该病的敏感度55.4%, 特异度64.8%; 以两种方法联合检测均阳性为诊断标准, 则敏感度52.5%, 特异度94.1%.结论测定血清CA125水平,对子宫腺肌病是较好的辅助诊断指标;B超检查对该病有一定诊断价值;两者联合检测能提高诊断的正确性,且方法简便、快捷、无创伤,是目前较为实用的诊断方法.

Clinical Evaluation of Ultrasonography and Serum CA125 in Diagnosis of Adenomyosis

Objective: To investigate the diagnostic value of ultrasonography and serum CA 125 in adenomyosis. Methods: 120 cases of adenomyosis and myoma of uterus were analysed. All cases were carried out the ultrasonography of type B and detected the serum CA 125 before operation, and then compared with the postoperative pathological examination which could make accurate diagnosis. Results: The positive rate and specificity of serum CA 125 for diagnosis of adenomyosis were 73.8% and 73.5%. The sensitivity and specificity of ultrasonography of type B for diagnosis of adenomyosis were 55.4% and 64.8%. If combining these two methods as diagnostic criteria, the sensitivity and specificity were 52.5% and 94.1%. Conclusions: The determination of serum CA 125 is helpful for the auxiliary diagnosis of adenomyosis. Ultrasonography is rather valuable for the diagnosis of adenomyosis. The diagnostic accuracy may be enhanced after combining them that provide quick, convenient, noninvasive, and practical diagnostic method.