| 氧氟沙星阴道泡腾片抗菌活性实验动物的研究 |
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| 引用本文： | 孙惠华,邵启祥,李良菊,许浒.氧氟沙星阴道泡腾片抗菌活性实验动物的研究[J].江苏大学学报(医学版),1998(3). |
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| 作者姓名： | 孙惠华 邵启祥 李良菊 许浒 |
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| 摘 要： | 采用氧氟沙星（ＯＦＬＸ）阴道泡腾片和诺氟沙星（ＮＦＬＸ）阴道栓对临床常见的细菌性阴道炎进行了动物体内外抗菌活性测定。结果显示：体外测定组：ＯＦＬＸ对致病菌的ＭＩＣ在０１～３１２μｇ／ｍｌ而ＮＦＬＸＭＩＣ与其相近。体内测定组：ＯＦＬＸ的治愈率２ｍｇ／ｋｇ组为５０％，４ｍｇ／ｋｇ和８ｍｇ／ｋｇ组为１００％。而ＮＦＬＸ栓２ｍｇ／ｋｇ组为４０％，４ｍｇ／ｋｇ组为８０％，８ｍｇ／ｋｇ组为１００％，空白组治愈率为０。说明ＯＦＬＸ阴道泡腾片对此类阴道炎具良好的疗效，低、中剂量组略优于ＮＦＬＸ栓。但两药无统计学差异
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| 关 键 词： | 氧氟沙星 诺氟沙星 MIC |
The Study of Anti-bacterial Action of OFLX Vaginal Effervescent Tablets In Vitro And Vivo |
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| Sun Huihua,Shao Qixiang,Li Liangjue,et al.The Study of Anti-bacterial Action of OFLX Vaginal Effervescent Tablets In Vitro And Vivo[J].Journal of Jiangsu University Medicine Edition,1998(3). |
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| Authors: | Sun Huihua Shao Qixiang Li Liangjue |
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| Institution: | Department of immunology |
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| Abstract: | |
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| Keywords: | OFLX NFLX MIC |
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