Differences in MBL levels between juvenile patients newly diagnosed with type 1 diabetes and their healthy siblings |
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| Authors: | Stine Mø ller Sildorf,Stefanie Eising,David M. Hougaard,Henrik Bindesbø l Mortensen,Kristin Skogstrand,Flemming Pociot,Jesper Johannesen,Jannet Svensson |
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| Affiliation: | 1. Pediatric Department, Herlev Hospital, Herlev Ringvej 75, 2730 Herlev, Denmark;2. Sønderborg Hospital, Sydvang 1, 6400 Sønderborg, Denmark;3. Danish Center for Neonatal Screening, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen S, Denmark;4. Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark |
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| Abstract: | The incidence of type 1 diabetes (T1D) has during the last few decades been increasing in children and juveniles. Multi-factorial courses combining genetic disposition and environmental factors might be in play, and through the years, there has been a mounting interest in the innate immune system's role in the development of T1D. |
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| Keywords: | Mannose binding lectin Type 1 diabetes Innate immune system Autoimmunity Pediatrics Cytokines |
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