| 格列齐特治疗非胰岛素依赖性糖尿病的疗效 |
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| 引用本文： | 罗邦,宁光,吴万龄,邵安华,高鑫,俞茂华. 格列齐特治疗非胰岛素依赖性糖尿病的疗效[J]. 中国新药与临床杂志, 1995, 0(4) |
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| 作者姓名： | 罗邦 宁光 吴万龄 邵安华 高鑫 俞茂华 |
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| 作者单位： | 上海第二医科大学附属瑞金医院内分泌科，上海第二医科大学附属第九人民医院，上海市第一人民医院，上海医科大学附属中山医院，上海医科大学附属华山医院 |
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| 摘 要： | 本文对国产和进口格列齐特各治疗８１和７６例非胰岛素依赖性糖尿病进行为期３－４ｍｏ的疗效对比。结果：２组的空腹和餐后血糖、ＨｂＡ１及血清三酰甘油（甘油三酯）明显降低，但空腹和餐后血清胰岛素和血清胆固醇没有明显变化。国产格列齐特的有效剂量明显低于进口格列齐特（Ｐ＜０．０５）。本文证明两者的疗效没有明显差别。
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| 关 键 词： | 格列齐特；非胰岛素依赖型糖尿病；血糖；胰岛素：胆固醇；三酰甘油类 |
Therapeutic effects of gliclazide in non-insulin-dependent diabetes mellitus |
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| LUO Bang-Yao, NING Guang,WU Wan-Ling,. Therapeutic effects of gliclazide in non-insulin-dependent diabetes mellitus[J]. Chinese Journal of New Drugs and Clinical Remedies, 1995, 0(4) |
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| Authors: | LUO Bang-Yao NING Guang WU Wan-Ling |
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| Abstract: | The therapeutic effects of domestic and imported gliclazide in 81 and 76 patients with NIDDM, respectively were compared during 3 -4 mo in this study. The results showed that the fasting and postprandial plasma glucose concentrations, HbA1 as well as the serum triglyceride were remarkably reduced in both domestic and imported gliclazide groups, but the fasting and postprandial serum insulin levels and serum cholesterollevel were not changed significantly. The effective dosage of domestic gliclazide was lower than that of imported gliclazide (P< 0.05). The study demonstrated that there was no significant difference between the effects of domestic and imported gliclazide. |
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| Keywords: | gliclazide non-insulin-dependent diabetes mellitus blood glucose insulin cholesterol triglycerides |
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