Ceramide composition of whole brain synaptosomal gangliosides from mice genetically bred for divergent ethanol sensitivities. |
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| Authors: | M D Ullman R F Ventura L J Draski R A Deitrich R C Baker |
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| Institution: | Research Service/GRECC, ENRM Veterans Hospital, Bedford, MA 01730. |
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| Abstract: | A comparison of the two major ceramide molecular species (d18:1-C18:0 and d20:1-C18:0) of synaptosomal gangliosides GM1, GD1a+GT1a, GD1b, GT1b, revealed a difference between the ceramide composition of ethanol-sensitive LS and ethanol-insensitive SS whole brain synaptosomal gangliosides. In all comparisons, the ratio of the two major molecular species, (d18:1-C18:0/d20:1-C18:0) was less for LS than for SS mice. |
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