18F-FDG PET与99Tcm-MDP骨显像在诊断肿瘤骨转移中的比较

恶性肿瘤发生骨转移将大大影响患者的生存率、降低患者的生活质量.PET和骨显像作为两种常见的评估全身骨骼情况的显像模式,能早期发现骨转移,进行肿瘤分期,帮助临床治疗.通过两种显像的原理,可以分析不同骨质破坏的病理类型的诊断差异和侧重点.除PET和骨显像之外,MRI也是灵敏度很高的影像学检查方法之一.此外,新型PET示踪剂的出现和PET-CT、SPECT-CT融合显像必将为核医学探测肿瘤骨转移提供新的价值.

Comparasion of 18F-FDG PET and 99Tcm-MDP bone imaging in diagnosis of bone metastasis

Bone metastasis from malignant tumor will reduce the survival rate and life quality of patients. As the most two common procedures of evaluating the condition of whole-body skeletal system, both 18F-FDG PET and 99Tcm-MDP bone imaging can detect early metastasis and stage the cancer, thus helping the treatment. With the help of the theory of these two imaging methods, diagnostic differences and points of focus in different pathological types of bone destruction can be analyzed. Except PET and bone imaging, MRI is also an imaging method with high sensitivity. Moreover, PET-CT, SPECT-CT and some newly-discovered tracers will certainly add new value on detecting bone metastasis by methods of nuclear medecine.