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Linfoma cutáneo primario difuso de células grandes-tipo pierna con regresión espontánea
Institution:1. Servicio de Dermatología, Hospital Universitario Ramón y Cajal, Madrid, España;2. Servicio de Anatomía Patológica, Hospital Universitario Ramón y Cajal, Madrid, España;1. Servicio de Dermatología, Hospital Universitario 12 de Octubre, Madrid, España;2. Servicio de Dermatología. Hospital Universitario La Paz, Madrid, España;1. Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom;2. Department of Pathology, Royal Liverpool University Hospital, Liverpool, United Kingdom;1. Department of Dermatology, Poznan University of Medical Sciences, Poland;2. Department of Haematology, Poznan University of Medical Sciences, Poland;3. Department of Microbiology, Poznan University of Medical Sciences, Poland;4. Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chalubinskiego 1, 50–368 Wroclaw, Poland;1. Clinic of Nuclear Medicine, Istanbul Training and Research Hospital, Fatih, Estambul, Turquía;2. University of Health Sciences, Clinic of Nuclear Medicine, Istanbul Training and Research Hospital, Fatih, Estambul, Turquía;3. Clinic of Pathology, Istanbul Training and Research Hospital, Fatih, Estambul, Turquía
Abstract:Primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL LT) accounts for approximately 20% of all primary cutaneous B-cell lymphomas and tends to present as infiltrated nodules, tumors, and plaques on the legs in the elderly. Unlike other primary cutaneous large B-cell lymphomas, it has a poor prognosis and tends to require treatment with systemic chemotherapy.We present the case of an 82-year-old patient with a 1-year history of nodules and plaques on her right leg. Biopsy led to a diagnosis of PCLBCL LT and the lesions resolved without treatment within 1 month of the first visit. This is an atypical course of PCLBCL LT and we believe that it is the first such case to be reported in the literature.
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