丁苯酞联合语言康复治疗对急性脑梗死后运动性失语患者神经功能及语言损伤恢复的影响研究

目的探讨丁苯酞联合语言康复治疗对急性脑梗死后运动性失语患者神经功能及语言损伤恢复的影响。方法选取2016年8-2019年5月于本院就诊的102例急性脑梗死后运动性失语患者为研究对象,随机分为观察组(51例)、对照组(51例)。对照组给予脑梗死后常规治疗,观察组在常规治疗的基础上使用丁苯酞联合语言康复治疗,对比两组患者治疗疗效及治疗前后的神经功能缺损评分(NIHSS)、失语指数(AQ)、曰常生活交流能力(CADL)及语言功能评分的水乎变化。结果观察组患者临床总有效率高于对照组(96.07%vs74.51%)(χ^2=9.220,P=0.002);治疗后两组患者AQ、CADL评分高于治疗前,NIHSS评分低于治疗前(P<0.05),且观察组治疗后AQ、CADL评分明显高于对照组,NIHSS评分低于对照组(P<0.05);治疗后两组患者语言功能各项指标水平均高于治疗前(P<0.05),且观察组各项指标水平明显高于对照组(P<0.05)。结论丁苯酞联合语言康复治疗脑梗死后运动性失语患者的临床疗效显著,可有效改善其神经功能缺损程度,促进语言功能恢复。

Effects of butylphthalide combined with speech rehabilitation on neurological function and recovery of language injury in patients with exercise aphasia after acute cerebral infarction

Objective To investigate the effects of butylphthalide combined with speech rehabilitation on the recovery of nerve function and language injury in patients with exercise aphasia after acute cerebral infarction.Methods 102 patients with exercise aphasia after acute cerebral infarction admitted to our hospital from August 2016 to May 2019 were selected as the study subjects and randomly divided into observation group(51 cases)and control group(51 cases).The control group received routine treatment after cerebral infarction,while the observation group received butylphthalide combined with speech rehabilitation therapy on the basis of routine treatment.The therapeutic effect of the two groups was compared with the changes in the levels of neurological deficit score(NIHSS),aphasia index(AQ),daily life communication ability(CADL)and language function score before and after treatment.Results The total effective rate in the observation group was higher than that in the control group(96.07%vs74.51%)(χ^2=9.220,P=0.002).After treatment,AQ and CADL scores of patients in the two groups were higher than those before treatment,and NIHSS scores were lower than those before treatment(P<0.05).Moreover,AQ and CADL scores in the observation group were significantly higher than those in the control group,and NIHSS scores were lower than those in the control group(P<0.05).After treatment,all the indicators of language function in the two groups were higher than those before treatment(P<0.05),and the indicators in the observation group were significantly higher than those in the control group(P<0.05).Conclusion:Butylphthalide combined with speech rehabilitation in the treatment of patients with exercise aphasia after cerebral infarction has a significant clinical effect,can effectively improve the degree of neurological impairment,promote the recovery of language function.