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PSMA配体PET显像在非前列腺肿瘤诊疗中的应用
引用本文:王观筠,于鹏,宁静,徐白萱. PSMA配体PET显像在非前列腺肿瘤诊疗中的应用[J]. 中华核医学与分子影像杂志, 2020, 0(4): 243-246
作者姓名:王观筠  于鹏  宁静  徐白萱
作者单位:解放军总医院核医学科
基金项目:国家自然科学基金(81571715)。
摘    要:前列腺特异膜抗原(PSMA)是前列腺癌分子影像学研究的热点.但PSMA也可在非前列腺的生理组织及其他多种良恶性疾病中表达,特别是在肿瘤相关的新生血管内皮细胞中高表达.相关临床研究已表明PSMA配体PET显像在指导非前列腺癌的其他恶性肿瘤分期中具有应用价值.该文对PSMA配体PET显像在非前列腺肿瘤诊断和治疗中的应用进行综述.

关 键 词:前列腺特异膜抗原  正电子发射断层显像术  发展趋势

Application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors
Wang Guanyun,Yu Peng,Ning Jing,Xu Baixuan. Application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors[J]. Chinese Journal of Nuclear Medicine, 2020, 0(4): 243-246
Authors:Wang Guanyun  Yu Peng  Ning Jing  Xu Baixuan
Affiliation:(Department of Nuclear Medicine,Chinese PLA General Hospital,Beijing 100853,China)
Abstract:Prostate specific membrane antigen(PSMA)is a hot topic in molecular imaging research of prostate cancer.However,non-prostate related PSMA can also be expressed in physiological tissues and different benign and malignant diseases,especially in tumor-associated endovascular endothelial cells.Related clinical studies have demonstrated the staging potential of PSMA ligands PET imaging in non-prostate tumors.This article summarizes the application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors.
Keywords:Prostate-specific membrane antigen  Positron-emission tomography  Trends
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