围生期孕妇生殖道B族链球菌感染的影响因素分析及对妊娠结局的影响

目的探究围生期孕妇生殖道B族链球菌(GBS)感染的影响因素分析及对妊娠结局的影响。方法选取50例围生期生殖道B族链球菌感染孕妇作为观察组,同时选取50例正常孕妇作为对照组。对围生期孕妇生殖道B族链球菌感染进行单因素分析和多因素Logistic回归分析,并比较两组不良妊娠结局。结果观察组孕妇年龄≥35岁、孕前检查、流产史、阴道炎、抗生素应用、新生儿检查的占比均显著高于对照组,差异均具有统计学意义(P<0.05)。两组孕妇初孕妇占比比较差异无统计学意义(P>0.05)。多因素Logistic回归分析显示,年龄≥35岁、有流产史、有阴道炎、无孕前检查、未应用抗生素及新生儿出生后未行相关检查均是围生期孕妇生殖道B族链球菌感染的危险因素,差异具有统计学意义(P<0.05)。观察组早产、胎膜早破、产褥感染、黄疸、肺炎、窒息、宫内窘迫发生率分别为30.00%、18.00%、12.00%、18.00%、12.00%、18.00%、14.00%,显著高于对照组的8.00%、2.00%、0、2.00%、0、2.00%、0,差异均具有统计学意义(P<0.05)。结论孕妇年龄≥35岁、有流产史、有阴道炎以及新生儿未行相关检查等都可能增加B族链球菌感染的发生风险,因此要重视并做好围生期孕妇生殖道B族链球菌的检查和预防工作,进而明显的改善母婴结局。

Analysis of influencing factors of group B streptococcus infection in reproductive tract of perinatal pregnant women and its influence on pregnancy outcome

Objective To investigate the influencing factors of group B streptococcus(GBS)infection in reproductive tract of perinatal pregnant women and its influence on pregnancy outcome.Methods There were 50 perinatal pregnant women with group B streptococcus infection in reproductive tract selected as the observation group,and another normal pregnant women as the control group.Single factor analysis and multiple factor Logistic regression analysis were used to analyze the infection of group B streptococcus in reproductive tract of pregnant women in perinatal period,and the adverse pregnancy outcomes of the two groups were compared.Results The proportion of≥35 years of age,pre-pregnancy examination,abortion history,vaginitis,antibiotic application,neonatal examination in the observation group were significantly higher than those in the control group,and their difference was statistically significant(P<0.05).There was no statistically significant difference in proportion of first pregnant women between the two groups(P>0.05).Multivariate logistic regression analysis showed that≥35 years of age,abortion history,vaginitis,no pre-pregnancy examination,no antibiotic application and no relevant examination after birth were all risk factors of group B streptococcal infection in perinatal pregnant women,and their difference was statistically significant(P<0.05).The incidence of preterm birth,prom,puerperal infection,jaundice,pneumonia,asphyxia and intrauterine distress in the observation group were 30.00%,18.00%,12.00%,18.00%,12.00%,18.00%and 14.00% respectively in the observation group,which were significantly higher than 8.00%,2.00%,0,2.00%,0,2.00% and 0 in the control group,and their difference was statistically significant(P<0.05).Conclusion The risk of group B streptococci infection may be increased by the age of pregnant women≥35 years old,abortion history,vaginitis and the absence of relevant examination in newborns.Therefore,it is necessary to pay attention to and do a good job in the inspection and prevention of group B streptococcus in the reproductive tract of pregnant women during perinatal period,so as to significantly improve the outcome of mother and child.