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Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells
Institution:1. Department of Microbiology & Immunology, Wake Forest School of Medicine, Winston-Salem, NC 27101, USA;2. Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA;3. Department of Mathematics and Statistics, St. Cloud State University, St Cloud, MN 56301, USA;4. Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA;5. Center for Translational Research in Hematologic Malignancies, Houston Methodist Cancer Center, Houston, TX 77030, USA
Abstract:
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  • Keywords:Adoptive cell therapy  Th9  type I IFN  antigen-loss variant cancer cells
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