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Signatures of plasticity,metastasis, and immunosuppression in an atlas of human small cell lung cancer
Institution:1. Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;2. Program for Computational and Systems Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10016, USA;3. Department of Medical Oncology; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Clinical Cooperation Unit Virotherapy; National Center for Tumor Diseases (NCT), Heidelberg, Germany;4. Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;5. Department of Computer Science, Columbia University, New York, NY 10027, USA;6. Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;7. Precision Pathology Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;8. Thoracic Service, Department of Surgery, Fiona and Stanley Druckenmiller Center for Lung Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;9. Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;10. Perlmutter Cancer Center, New York University Langone Health, New York, NY 10065, USA;11. Institute of Biotechnology, Vilnius University, Vilnius, Lithuania;12. Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA;13. Weill Cornell Medical College, New York, NY 10065, USA
Abstract:
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  • Keywords:SCLC  metastasis  scRNA-seq  tumor atlas  single cell  PLCG2  myeloid
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