Gastrointestinal quality of life before and short- and long-term after Roux-en-Y gastric bypass for severe obesity |
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| Institution: | 1. Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland;2. Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland;3. Department of Surgery, Riviera-Chablais Hospital, Rennaz, Switzerland;4. Department of Visceral Surgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland;1. Department of General Surgery, Temple University Hospital, Philadelphia, Pennsylvania;2. Department of Minimally Invasive and Bariatric Surgery, Temple University Hospital, Philadelphia, Pennsylvania;3. Department of Clinical Sciences, Temple University Hospital, Philadelphia, Pennsylvania;4. Department of Medical Genetics and Molecular Biochemistry, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania;1. Department of Surgery, Geisinger Wyoming Valley Medical Center, Wilkes Barre, Pennsylvania;2. Department of Surgery, Geisinger Medical Center, Danville, Pennsylvania;3. Department of Surgery, Geisinger Community Medical Center, Scranton, Pennsylvania;1. Department of General Surgery, Cleveland Clinic, Weston, Florida;2. The Bariatric and Metabolic Institute, Cleveland Clinic, Weston, Florida |
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| Abstract: | BackgroundOverall quality of life (QoL) is generally improved after bariatric surgery. Gastrointestinal (GI) symptoms including abdominal pain have been reported in up to >30% of patients after Roux-en-Y gastric bypass (RYGB), and may negatively influence QoL, especially GI-QoL.ObjectivesTo evaluate the evolution of GI symptoms and GI-QoL short- and long-term after RYGB.SettingTwo public hospitalsMethodsCandidates for bariatric surgery (n = 128, BMI = 44.2 ± 7.4) or patients who had undergone RYGB 2–4 years (n = 161, BMI = 29.3 ± 15.9) and 5–10 years (n = 121, BMI = 31.3 ± 6.5) before were invited to complete a questionnaire combining 3 validated questionnaires (GIQLI, GSRS, and PCS) specifically designed to evaluate GI-QoL. Scores were compared between the preoperative, early, and late postoperative periods.ResultsThe GIQLI score improved from 88.1 before surgery to 118.6 (P < .0001) and 109.7 (P < .0001) in the early and late postoperative periods respectively. GSRS score improved from 15.6 to 10.1 (P = .0001) and 12.8 (P = .012), and PCS-score improved from 19 to 4.5 (P = .0001) and 8.3 (P = .0001), respectively. The GI subscore of the GIQLI improved from 57.4 to 62.1 (P = .007) in the early period but was not significantly different in the late period (59.3 versus 57.4, P = .3). The psychological impact of GI symptoms decreased at both postoperative time points.ConclusionGI-QoL is markedly improved after RYGB, and this improvement persists up to 10 years. GI symptoms decrease early after surgery and do not worsen in the longer term. Their psychological impact is markedly reduced. |
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| Keywords: | Roux-en-Y gastric bypass Quality of life GIQLI GSRS PCS Obesity |
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