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低分子肝素预防青光眼并白内障三联术后炎症反应
引用本文:杜建英,王晓玲,赵吉飞,关小荣,陈小琪. 低分子肝素预防青光眼并白内障三联术后炎症反应[J]. 国际眼科杂志, 2008, 8(11): 2332-2333
作者姓名:杜建英  王晓玲  赵吉飞  关小荣  陈小琪
作者单位:中国陕西省咸阳市第一人民医院眼科,712000;陕西省中医学院附属医院,中国陕西省西安市,710003
摘    要:目的:研究低分子肝素对青光眼合并白内障联合人工晶状体植入手术(简称三联术)后炎症反应的预防作用。方法:将52例青光眼合并白内障随机分为2组,并盲法给药。在三联手术中,对照组灌注液为9g/L氯化钠注射液,低分子肝素组(LMWH)在9g/L氯化钠灌注液中加入博璞青(low molecular weijht heparin calcium injection)浓度为5U/mL,术后2,4,7d观察眼内纤维蛋白渗出,房水混浊情况。结果:LMWH组术后2,4,7d,眼内纤维蛋白的渗出及膜形成,房水混浊程度明显较对照组轻(P<0.05)。结论:LMWH能有效抑制三联术后眼内炎症反应。

关 键 词:三联手术后  低分子肝素  炎症反应

Research on the prevention effect of low molecular weight heparin on inflammatory response after glaucoma with cataract combined with introcular lens implantation
Jian-Ying Du,Xiao-Ling Wang,Ji-Fei Zhao,Xiao-Rong Guan,Xiao-Qi Chen. Research on the prevention effect of low molecular weight heparin on inflammatory response after glaucoma with cataract combined with introcular lens implantation[J]. International Eye Science, 2008, 8(11): 2332-2333
Authors:Jian-Ying Du  Xiao-Ling Wang  Ji-Fei Zhao  Xiao-Rong Guan  Xiao-Qi Chen
Affiliation:Jian-Ying Du1,Xiao-Ling Wang2,Ji-Fei Zhao1,Xiao-Rong Guan1,Xiao-Qi Chen11 Department of Ophthalmology,the First People's Hospital of Xianyang City,Xianyang 712000,Shaanxi Province,China,2 Department of Oph-thalmology,the Affiliated Hospital of Chinese Traditional Medicine,Xi'an 710003
Abstract:AIM:To research the prevention effect of low molecular weight heparin (LMWH) on inflammatory response after glaucoma with cataract combined with introcular lens implantation (triplex operations).·METHODS:Fifty-two glaucoma cases combined with cataract were randomly divided into 2 groups and were treated with medicine blindly.During triplex operations,control group was given 9g/L NaCl injection and LMWH group received 9g/L NaCl injection adding low molecular weight heparin calcium injection 5U/mL.Postoperative day 2,4 and 7,the condition of intraocular fibrin exu-dation,membrane formation and acqueous opacity were observed.·RESULTS:On day 2,4 and 7 after surgery,the degree of intraocular fibrin exudation,membrane formation and acqueous opacity in LMWH group was lighter then that in control group (P<0.05).·CONCLUSION:LMWH can effectively inhibit inflam-matory response in eyes after triplex operations·
Keywords:triplex operations  low molecular weight heparin  inflammatory response  
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