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Comparative in vitro activity of the new oxacephem antibiotic,flomoxef (6315-S)
Authors:G. Ruckdeschel  W. Eder
Affiliation:(1) Max von Pettenkofer-Institute for Hygiene and Medical Microbiology, Klinikum Grosshadern, University of Munich, Marchioninistrasse 15, 8000 Munich 70, FRG
Abstract:The in vitro activity of flomoxef (6315-S) was determined and compared to that of different cephalosporins against 787 clinical isolates of staphylococci,Enterobacteriaceae and anaerobes. Flomoxef is similar in activity to latamoxef and cefotaxime againstEnterobacteriaceae, slightly more active than cephalothin and cefamandole against oxacillin-sensitive strains ofStaphylococcus aureus and minimally less active than cefamandole against oxacillin-resistant strains. Flomoxef showed similar or better activity than latamoxef and cefoxitin against most of the anaerobic species of medical importance.
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