| 乙型肝炎肝硬化自发性细菌性腹膜炎患者T细胞亚群的研究 |
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| 引用本文： | 王玲,张才军,李惠琴,谢蒲伶,周曾全,邓学端. 乙型肝炎肝硬化自发性细菌性腹膜炎患者T细胞亚群的研究[J]. 昆明医学院学报, 2004, 25(3): 1-3 |
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| 作者姓名： | 王玲 张才军 李惠琴 谢蒲伶 周曾全 邓学端 |
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| 作者单位： | 1. 昆明医学院微生物学与免疫学教研室,昆明,650031
2. 昆明市第三人民医院肝病研究室,昆明,650041 |
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| 基金项目： | 昆明市科技局和昆明市卫生局科研基金资助课题 |
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| 摘 要： | 目的 :对 136例乙型肝炎肝硬化自发性细菌性腹膜炎患者的T淋巴细胞进行了研究 .方法 :采用间接荧光法检测了患者的T淋巴细胞亚群 (CD+ 3 ,CD+ 8和CD+ 4 /CD+ 8) .结果 :患者T淋巴细胞亚群表现为严重紊乱 ,与正常对照组比较 ,CD+ 3 T淋巴细胞明显下降 (P <0 0 1) ,CD+ 8T淋巴细胞明显升高 (P <0 0 1) ,导致CD+ 4 /CD+ 8明显降低 (P <0 0 1) .结论 :乙型肝炎肝硬化自发性细菌性腹膜炎患者的T淋巴细胞亚群紊乱 ,而使免疫功能紊乱 ,这对指导临床治疗和判断预后具有重要意义
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| 关 键 词： | 患者 自发性细菌性腹膜炎 乙型肝炎肝硬化 T淋巴细胞亚群 CD3^＋ CD4^＋／CD8^＋ T细胞亚群 结论 指导 重要意义 |
| 文章编号： | 1003-4706(2004)03-0001-03 |
| 修稿时间： | 2003-10-20 |
Study of T Lymphocyte Subpopulations in Patients with Hepatitis B Liver Cirrhosis Spontaneous Bacterial Peritonitis |
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| WANG Ling ),ZHANG Cai-jun ),LI Hui-qin ),XIE Pu-ling ),ZHOU Zeng-quan ),DEDG Xue-duan ). Study of T Lymphocyte Subpopulations in Patients with Hepatitis B Liver Cirrhosis Spontaneous Bacterial Peritonitis[J]. Journal of Kunming Medical College, 2004, 25(3): 1-3 |
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| Authors: | WANG Ling ) ZHANG Cai-jun ) LI Hui-qin ) XIE Pu-ling ) ZHOU Zeng-quan ) DEDG Xue-duan ) |
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| Affiliation: | WANG Ling 1),ZHANG Cai-jun 1),LI Hui-qin 2),XIE Pu-ling 1),ZHOU Zeng-quan 2),DEDG Xue-duan 1) |
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| Abstract: | Objective: To study T lymphocyte subpopulations in 136 cases with hepatitis B liver cirrhosis spontaneous bacterial peritonitis. Methods: It was detected by indirect fluorescence assay that T lymphocyte subpopulations (CD + 3,CD + 8 and CD + 4/CD + 8) of the patients. Results: T lymphocyte subpopulations of the patients were serious disorder. Compared with normal, CD + 3 T lymphocyte subpopulations was decreased significantly (P<0.01), CD + 8 was increased obviously (P<0.01), whereas CD + 4/CD + 8 was reduced obviously (P<0.01). Conclusion: T lymphocyte subpopulations were disorder in the patients with hepatitis B liver cirrhosis spontaneous bacterial Peritonitis. It results in disorder of immune functions. It has guiding significance for clinical therapy and prognostic judgement. |
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| Keywords: | Hepatitis B Liver cirrhosis Spontaneous bacterial peritonitis T lymphocyte subpopulations |
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