A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk |
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Authors: | Zheng Jiang Chunxiang Li Ye Xu Sanjun Cai |
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Affiliation: | (1) Department of Colorectal Surgery, Cancer Hospital, Fudan University, 270 Dong An Road, Shanghai, 200032, China;(2) Laboratory of Medical Genetics, Harbin Medical University, 194 XueFu Road, Harbin, 150081, China; |
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Abstract: | Purpose Studies on polymorphism of X-ray repair cross-complementing group 1 (XRCC1), group 3 (XRCC3), and colorectal cancer risk are inconclusive. The purpose of this study is to evaluate the role of XRCC1 R399Q, R194W, and XRCC3 T241M genotypes in colorectal cancer susceptibility. |
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