Treatment of dementia with Lewy bodies |
| |
Authors: | Lebert F Le Rhun E |
| |
Affiliation: | Centre de la Mémoire, EA 2691, Clinique Neurologique, H?pital Roger Salengro, Centre Hospitalier Universitaire, Lille. f-lebert@chru-lille.fr |
| |
Abstract: | Dementia with Lewy bodies (DLB) is known for its partial resistance and hypersensitivity to some treatments, but DLB is treatable with cholinesterase inhibitors, sometimes better than in Alzheimer's disease. Cholinesterase inhibitors have a symptomatic effect on cognition and behavior. Nevertheless, new antipsychotics are sometimes also useful to manage psychotic symptoms. Although DLB patients respond less well to levodopa than patients with Parkinson's disease, 75 percent of DLB patients improve with levodopa, which is the best-tolerated dopaminergic agent. Nonpharmacological strategies include speech therapy, physiotherapy, psychotherapy, and educational support groups for care givers. |
| |
Keywords: | Démence à corps de Lewy Inhibiteurs de la cholinestérase Antipsychotiques L-Dopa |
本文献已被 ScienceDirect PubMed 等数据库收录! |
|