Serum and Saliva Ig-levels in Infants of Non-Atopic Mothers Fed Breast Milk or Cow's Milk-based Formulas |
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Authors: | P AA ØSTERGAARD |
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Institution: | Department of Paediatrics, Aalborg Hospital North, Aalborg, Denmark |
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Abstract: | ABSTRACT. Of twenty-five healthy, full term infants without a family history of atopic diseases, 13 were exclusively breast-fed from birth for a minimum of 3½ months (median 4½ months), whereas the remaining 12 infants were fed with cow's milk-based formulas from birth for a minimum of 4 months. In the latter group of children a significant increase in serum IgE as well as in salivary IgA was found. In infants exclusively breast-fed, no increase in serum IgE was seen until 6 months of age; at nine months of age, salivary IgA was still significantly lower than in the infants fed cow's milk-based formulas. No children developed obvious allergic diseases during the first three years of life. Thus, cow's milk proteins given to newborn children of non-atopic mothers did not seem to increase the risk of IgE-mediated diseases, maybe due to the development of "blocking" IgA-antibodies in the alimentary tract. |
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Keywords: | Breast- and cow's milk feeding infants of non-atopic mothers serum IgE saliva IgA |
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