DM2及伴微血管病变患者外周血白细胞水平分析

目的：外周血WBC是否参与了2型糖尿病（DM2）及微血管病变的发生发展。方法：受试者分为正常对照、无并发症DM2、伴微血管病变DM2等3组,检测正常对照组及DM2患者外周血WBC及代谢综合征相关指标,t检验分析组间WBC水平的差异,spearman相关分析DM2患者WBC水平与其他指标的相关性。结果：无并发症及微血管病变并发症DM2 WBC水平显著高于正常对照者,t值分别为3.08、2.94,P〈0.05,但无并发症与微血管病变DM2间WBC无显著性差异,t=0.89,P〉0.05;相关分析显示,WBC计数与年龄、体重指数（BMI）、三酰甘油（TG）、2h血糖（PBG）、2h胰岛素呈正相关,r值分别为0.248、0.201、0.435、0.225、0.352,P均〈0.05。结论：外周血WBC可能参与DM2及微血管病变的发生发展,WBC计数一定程度上可作为预测DM2发生的一个指标。

Study on the Peripheral White Boold Cell Count in Patients with Type 2 Diabetes Complicated with Microangiopathy

Objective To study the possible role played by peripheral white blood cells in the development of type 2 diabetes(DM2) and complication of microvascular pathological changes.Methods White blood cell count and metabolism related paratmeters(FBG,2hPBG,2h Pinsulin,TCH,HDL,LDL,TG,HbA1c,BMI,age) were examined in 33 DM2 patients without complication,41 DM2 patients with micro-angiopathy and 31 controls.Results The white blood cell counts in both DM2 patients with no complication and the DM2 with microvascular pat...