| 蛇床子素和蛇床子总香豆素对肾阳虚大鼠血清甲状腺激素和促甲状腺激素的影响 |
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| 引用本文： | 秦路平,张汉明,张卫东,张家庆,乔德彪.蛇床子素和蛇床子总香豆素对肾阳虚大鼠血清甲状腺激素和促甲状腺激素的影响[J].中国中西医结合杂志,1996,16(9):552-553. |
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| 作者姓名： | 秦路平 张汉明 张卫东 张家庆 乔德彪 |
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| 作者单位： | 第二军医大学药学院 |
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| 摘 要： | 采用醋酸氢化可的松造成肾阳虚模型大鼠，以它床子素和蛇床子总香豆素给药，测定大鼠血清促甲状腺激素和三种甲状腺激素Ｔ３，反Ｔ３及Ｔ４的浓度。结果，肾阳虚模型大鼠与正常大鼠比较，ＴＳＨ，Ｔ３，ｒＴ３和Ｔ４都显著降低；
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| 关 键 词： | 蛇床子素 蛇床子总香豆素 肾阳虚 大鼠 甲状腺素 |
Effect of Osthol and Total Coumarins of Fructus Cnidii on Thyroid Hormone and Thyrotropic Hormone in Kidney-Yang Deficiency Rats |
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| Abstract: | Osthol and total coumarins of Fructus Cnidii were given to the model of Kidney-Yang Deficiency rats induced by hydrocortison acetate injection, the changes of serum concentration of thyroxine T3,reverse T3 (rT3). T4 and thyroid stimulating hormone (TSH) were observed. Results showed that in comparison with normal rats, all of the criteria mentioned above were lowered significantly (P<0. 01) in model rats. After treatment, the criteria observed were all increased significantly (P<0.01 or P<0.05). It was suggested that the osthol and total coumarins of Fructus Cnidii could elevate the pituitary-thyroid axis function of. Kidney-Yang Deficiency rats. |
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| Keywords: | Fructus Cnidii osthol total coumarin modelof Kidney-Yang Deficiency thyroxin thyroid stimulating hormone |
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