中药热毒清对兔急性肺损伤的保护作用

采用静脉注射内毒素造成兔急性肺损伤的模型，观察热毒清对其治疗的效果。结果发现热毒清能明显抑制内毒素所引起的兔动脉血ｐＨ值，二氧化碳分压，肺体指数，肺湿干重，肺泡灌洗液内蛋白含量及白细胞总数手升高和动脉血氧分压的下降，并改善病理变化。

Protective Effect of Reduqing Injection on Rabbits with Acute Lung Injury

Acute lung injury(ALI) of rabbits was induced by endotoxin and the effects of Reduqing (RDQ) injection on the following indexes were studied. The results showed that the arterial blood PH,PCO2,lung/body index, lung wet/dry weight ratio, the protein and neutrophil contents in bronchoalveolar lavage fluid increased significently together with arterial PO2 marked drop, which were consistent with lung tissue damage, while administration of RDQ simultaneously ameliorated these changes. It is suggested that the Chinese herbal medicine RDQ injection could protect rabbit from the endotoxin-induced ALI.