Effects of regulatory peptides on changes in the content of brain stem catecholamine in rats during hypoxia and hemorrhage |
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| Authors: | A. G. Platonov E. N. Goncharenko Ya. V. Krushinskaya N. Yu. Kudryashova N. A. Sokolova |
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| Affiliation: | (1) Department of Biophysics, Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Moscow |
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| Abstract: | Effects of regulatory peptides FMRFa, thyroliberin, and Semax (ACTH4–10 analogue) on changes in the content of biogenic amines in rat brain stem observed 1 and 20 min after termination of hypoxia and 5 min after bloodletting (hemorrhage) were studied. The content of norepinephrine decreased to 82% of the control level 20 min after hypobaric hypoxia, while preliminary administration of the peptide complex abolished this effect. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 11, pp. 518–520, November, 1999 |
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| Keywords: | hypobaric hypoxia hemorrhage biogenic amines brain stem |
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