双胎输血综合征诊治的研究

双胎输血综合征(TTTS),多发生在单绒毛膜双羊膜双胎(DiMo)。由于发病机制尚未完全明确,因此在临床诊断及治疗上还存在一定的困难,目前单绒毛膜双羊膜双胎围生儿病死率为46%。虽然至今在诊断治疗方面有了一些进步,但产前诊断的主要方法仍然是B超。单绒毛膜双羊膜双胎若得不到治疗最终结局几乎均为极不成熟早产,治疗方法目前遵循的仍然是羊水减量应用最广泛,胎儿镜下激光凝固胎盘血管交通支(FLOC)治疗效果好,但是基于目前的设备及技术问题在临床上尚难推广。

Progress in Diagnosis and Treatment of Twin-to-twin Transfusion Syndrome

Twin-to-Twin Transfusion Syndrome (hereafter referred as “TTTS”) is the disease mostly happened to Diamniatie monochocionic twin (hereafter named as “DiMo”).Due to the uncertainty of the pathogenesis,we still have difficulty in the clinic diagnosis and treatment.At present,the perinatal mortality of DiMo accounts for 46 percent.Although we have made some progress in the diagnosis and treatment,B-mode ultrasonic examination is still the mostly applied antenatal diagnosis.Failure in treatment of the DiMo will result in the premature birth.However,decreasing amniotic fluid is still the most popular treatment since there are also some problem in the clinic spread of the facility and technology of the Fetoscope photocoagulator placenta FLOC,which may get a better curative effect.