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300例不同剂量乙肝疫苗接种后免疫效果观察
引用本文:周玉霞,万宝美.300例不同剂量乙肝疫苗接种后免疫效果观察[J].泰山医学院学报,1997,18(2):99-101.
作者姓名:周玉霞  万宝美
作者单位:Dept. of Infectious Disease,Taishan Medical College
摘    要:观察300例不同剂量,不同年龄,不同性别,不同免疫水平的患者,注射乙肝疫苗。方法按0,1,6mo程序,三角肌内注射,全程后6mo检测表面抗体。结果 表明乙肝疫苗剂量大与小产生表面抗体的阳转率无显著性差异。

关 键 词:乙肝疫苗  剂量  表面抗体  免疫  乙型肝炎

OBSERVATION OF IMMUNOLOGIC EFFECTS ON 300 CASES AFTER INOCULATION WITH DIFFERENT DOSES OF HEPATITIS B VACCINE
Zhou Yuxia,Wan Baomei,Yin Yanming,Zhang Yujiang,Chen Xianrei.OBSERVATION OF IMMUNOLOGIC EFFECTS ON 300 CASES AFTER INOCULATION WITH DIFFERENT DOSES OF HEPATITIS B VACCINE[J].Journal of Taishan Medical College,1997,18(2):99-101.
Authors:Zhou Yuxia  Wan Baomei  Yin Yanming  Zhang Yujiang  Chen Xianrei
Abstract:Objective To observe the immunologic effects on 300 cases in different ages and sexes and at different immunologic levels after having injected different doses of hepatitis B vaccine. Methods The different doses of hepatitis B vaccine were injected into musculus deltoideus according to 0, 1 and 6 month program. And anti-HBs were tested 6 months after the injection. Results The positive rate of anti-HBs wasn't significant associated with dose (PWTBZ]>0.05) but with age, sex and body's immunologic level (P<0.01). Conclusion This suggests that immunologic effects aren't related to dose but to age, sex and body's immunologic level.
Keywords:hepatitis B vaccine  dose  immunologic effect
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