布地奈德联合异丙托溴铵治疗支气管哮喘急性发作期的疗效及对肺功能的影响

目的 探讨布地奈德联合异丙托溴铵治疗支气管哮喘急性发作期的疗效及对肺功能的影响.方法 选取2019年3月至2020年3月期间来我院治疗的支气管哮喘急性发作期患者105例作为研究对象,按照随机数字表法分为对照组(n=52)与研究组(n=53),两组均给予吸氧、抗感染、平喘、化痰等常规治疗措施,对照组在常规治疗基础上采用沙...

Therapeutic effect of budesonide combined with ipratropium bromide on acute attack of bronchial asthma and its effect on pulmonary function

Objective To investigate the therapeutic effect of budesonide combined with ipratropium bromide on acute attack of bronchial asthma and its effect on the pulmonary function.Methods A total of 105 patients with bronchial asthma in the acute attack phase who were treated in our hospital from March 2019 to March 2020 were collected as the research subjects.According to the random number table method,they were divided into the control group(n=52)and the research group (n=52).Both groups were given routine treatment measures such as oxygen inhalation,antiinfection,antiasthmatic,and phlegm resolving.The control group was treated with salbutamol on the basis of conventional treatment,and the research group was treated with salbutamol,budesonide combined with ipratropium bromide on the basis of conventional treatment.Clinical efficacy,pulmonary function indexes (PEF,FEV1%,FEV1/FVC) and clinical symptom remission times (cough,chest distress,shortness of breath,wheezing) were compared between the two groups.Results The total effective rates of treatment were 94.3%,which higher than in the research group of 78.8% the difference between the two groups was statistically significant(P<0.05).After treatment,pulmonary function indexes (PEF,FEV1%,FEV1/FVC) in the research group were higher than those in the control group,and the difference between the two groups was statistically significant (P<0.05).The clinical symptom remission time (cough,chest distress,shortness of breath,wheezing) in the research group was shorter than that in the control group,and the difference between the two groups was statistically significant(P<0.05).Conclusion Budesonide combined with ipratropium bromide has a better effect in the treatment of acute attack of bronchial asthma,which can quickly relieve the clinical symptoms and signs of patients and improve the lung function of patients.