影响老年急性基底动脉闭塞患者机械取栓临床预后的危险因素分析

目的探讨影响老年急性基底动脉闭塞患者机械取栓临床预后的危险因素分析。方法选取2018年3月至2020年3月期间在我院接受机械取栓治疗的62例老年急性基底动脉闭塞患者作为临床研究对象,观察两组相关资料,并通过多因素Logistic回归分析对影响预后的因素进行分析,研究对该疾病患者预后生存造成影响的高危因素。结果经单因素分析得出,两组患者症状性颅内出血发生率、血栓位置、发病至穿刺时间、吸烟史、合并症、年龄、性别比较,差异无统计学意义(P0.05);预后良好组患者侧支循环分级、血管再通分级显著优于预后不良组,差异有统计学意义(P0.05);预后良好组患者入院、治疗24 h、治疗1个月后NIHSS评分、血栓长度以及手术时间均显著低于预后不良组,差异有统计学意义(P0.05);将上述单因素均纳入Cox比例风险模型分析得出,侧支循环分级以及治疗24 h NIHSS评分均为对患者预后生存期影响的高危因素。结论影响老年急性基底动脉闭塞患者机械取栓临床预后的危险因素主要为侧支循环分级以及治疗1 d后的NIHSS评分,应加强对这两项的监测,以为患者的预后生存质量做出保障。

Analysis on the risk factors impacting the clinical prognosis of elderly patients with acute basilar artery occlusion after mechanical embolectomy

Objective?To explore the risk factors impacting the clinical prognosis of elderly patients with acute basilar artery occlusion after mechanical embolectomy.Methods?In this research,a total of 62 elderly patients with acute basilar artery occlusion undergoing mechanical embolectomy admitted to our hospital from March 2018 to March 2020 were selected as the clinical research objects.The related data of the two groups were observed,and the impacting factors of prognosis were analyzed through multivariate logistic regression analysis.Meanwhile,the high-risk factors impacting the prognosis and survival of patients with this disease were researched and analyzed.Results?Univariate analysis showed that there were no statistically significant differences in the incidence of symptomatic intracranial hemorrhage,thrombus location,time from onset to puncture,smoking history,complications,age and gender between the two groups(P>0.05).The classifications of collateral circulation and vascular recanalization in patients with good prognosis were significantly superior to those in patients with poor prognosis,with statistically significant differences (P<0.05).The NIHSS score,thrombus length and operation time of patients in the good prognosis group were significantly lower than those of patients in the poor prognosis group,with statistically significant differences (P<0.05).The above single factors were included in the Cox proportional hazards model analysis,and it was concluded that collateral circulation classification and NIHSS score after 24 h treatment were high risk factors impacting the prognosis and survival time of patients.Conclusion?The main risk factors impacting the clinical prognosis of elderly patients with acute basilar artery occlusion after mechanical embolectomy are collateral circulation classification and NIHSS score after one day of treatment.The monitoring of these two items should be strengthened,so as to ensure the prognosis and quality of life of patients.