缺血修饰白蛋白和肌红蛋白对急性冠状动脉综合征的早期诊断价值

目的:探讨血清缺血修饰白蛋白(IMA)和肌红蛋白(MYO)在急性冠状动脉综合征(ACS)早期诊断中的价值.方法:选取2019年1-6月在我院胸痛中心诊治的133例患者作为试验组:按胸痛发作至采血时间分为＜3h组、3～6h组和6～12 h组;按胸痛原因分为非缺血性胸痛(NICP)组和ACS组(按不同表现分为UA组、NST...

Value of ischemia modified albumin and myoglobin in early diagnosis of acute coronary syndrome

Objective:To investigate the value of serum ischemia modified albumin(IMA)and myoglobin(MYO)in the early diagnosis of acute coronary syndrome(ACS).Methods:133 patients diagnosed and treated in Chest Pain Center of our hospital from January to June 2019 were selected as the experimental group:according to the time from chest pain to blood collection,they were divided into<3 h group,3-6 h group and 6-12 h group;according to the cause of chest pain,they were divided into non ischemic chest pain(NICP)group and ACS group(according to the different performance,they were further divided into UA group,NSTEMI group and STEMI group),and 30 healthy subjects were randomly selected as control group.The serum concentrations of IMA and MYO were measured to evaluate their value in the early diagnosis of ACS.Results:The levels of IMA and MYO in UA group,NSTEMI group and STEMI group were higher than those in the control group(P<0.05 or P<0.01).The levels of serum IMA and MYO in<3 h group,3-6 h group and 6-12 h group were also higher than those in the control group(P<0.05).The sensitivity and accuracy of IMA combined with MYO in the diagnosis of ACS were 92.16%and 85.71%,respectively.Conclusion:IMA combined with MYO can greatly improve the sensitivity and accuracy in the diagnosis of ACS,exclude the patients with NICP as soon as possible,and has a certain value in the early diagnosis of ACS.