真武汤联合左旋甲状腺素片治疗亚临床甲状腺功能减退症孕妇妊娠的效果

目的 探讨真武汤联合左旋甲状腺素对亚临床甲状腺功能减退症孕妇妊娠结局的影响.方法 选取2017年1月至2019年1月在我院收治的亚临床甲状腺功能减退症孕妇132例作为研究对象,应用随机数字表分为西药组和中西药联合组,每组各66例.西药组孕妇给予左旋甲状腺素进行治疗,中西药联合组给予真武汤联合左旋甲状腺素进行治疗.评估两...

Effect of Zhenwu Decoction and levothyroxine tablets on the pregnancy of women with subclinical hypothyroidism

Objective To investigate the effect of Zhenwu Decoction combined with levothyroxine on pregnancy outcome of pregnant women with subclinical hypothyroidism.Methods A total of 132 pregnant women with subclinical hypothyroidism who were admitted to our hospital from January 2017 to January 2019 were selected as the research subjects.They were divided into the western medicine group and the Chinese and western medicine combination group using a random number table,with 66 cases in each group.Pregnant women in the western medicine group were given levothyroxine for treatment.The Chinese and western medicine combination group were given Zhenwu Decoction combined with levothyroxine for treatment.The clinical effects and pregnancy outcomes between the two groups were evaluated.The TCM symptom scores,folic acid,and serum thyroid hormone levels between the two groups before and after treatment were compared.Results After treatment,the total clinical effective rates of pregnant women in the western medicine group was 96.97%,which was higher than that of 77.27% in the Chinese and western medicine combination group.The difference between the two groups was statistically significant (P<0.05).After treatment,the scores of thyroid pain,fatigue,memory decline,and irritability in the two groups were significantly lower than before treatment,and the difference was statistically significant(P<0.05).However,there was no significant difference in the levels of FT3 and FT4 after the treatment between the two groups(P>0.05).After the treatment,the TSH level in the Chinese and western medicine combination group was significantly lower than that in the control group,and the folic acid level was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).After the treatment,the total incidence of adverse pregnancy outcomes for pregnant women in the western medicine group was 18.18%,which was higher than that of 4.55% in the Chinese and western medicine combination group.The difference between the two groups was statistically significant(P<0.05).Conclusion Zhenwu Decoction combined with levothyroxine has a significant effect in the treatment of pregnant women with subclinical hypothyroidism,which can improve the clinical symptoms of the patients,reduce the TSH level and the incidence of adverse pregnancy outcomes.