集束化护理在行双重血浆分子吸附系统治疗肝衰竭患者中的应用

目的 探讨集束化护理在行双重血浆分子吸附系统（DPMAS）治疗肝衰竭患者中的应用效果。方法 选取2018 年1 月至2019 年12 月我院收治的肝衰竭患者68 例作为研究对象，按随机数字表法分为对照组及试验组，每组各34 例。两组均施以一般药物、DPMAS 治疗，对照组给予常规护理，试验组给予集束化护理，比较两组患者TBiL、ALT、CHE、PTA、住院时间、死亡率、导管相关感染及异常出血的发生率。结果 干预前后两组患者TBiL、CHE 比较，差异有统计学意义（P<0.05）；干预前后两组患者ALT、PTA 比较，差异无统计学意义（P>0.05）；干预前两组患者TBiL、ALT、CHE、PTA 指标比较，差异无统计学意义（P>0.05）；干预后两组患者TBiL、ALT、CHE、PTA 比较，差异无统计学意义（P>0.05）；然而，试验组住院时间显著短于对照组，差异有统计学意义（P<0.05）；试验组患者死亡率、导管相关感染发生率、异常出血发生率显著低于对照组，差异有统计学意义（P<0.05）。结论 集束化护理在行DPMAS 治疗肝衰竭患者中能够显著降低导管相关感染及异常出血发生率，缩短住院时间，具有一定的临床推广价值。

Application of bundle nursing in the treatment of patients with liver failure with double plasma molecular adsorption system

Objective To investigate the application effect of bundle nursing in the treatment of patients with liver failure with double plasma molecular adsorption system (DPMAS).Methods A total of 68 patients with liver failure admitted to our hospital from January 2018 to December 2019 were selected as the study objects,and they were divided into the control group and the experimental group,with 34 cases in each group according to the random number table method.Both groups were treated with general drugs and DPMAS.The control group was treated with conventional nursing,while the experimental group was treated with bundle nursing.TBiL,ALT,CHE,PTA,hospitalization time,mortality,the incidence of catheter related infection and abnormal hemorrhage were compared between the two groups.Results There were statistically significant differences in TBiL and CHE between the two groups before and after intervention (P<0.05).There were no statistically significant differences in ALT and PTA between the two groups before and after intervention(P>0.05).Before intervention,there were no statistically significant differences in TBiL,ALT,CHE and PTA indices between the two groups (P>0.05).There were no statistically significant differences in TBiL,ALT,CHE and PTA between the two groups after intervention(P>0.05).However,the hospitalization time in the experimental group was significantly shorter than that in the control group,with statistically significant difference (P<0.05).The mortality,incidence of catheter related infection and abnormal hemorrhage in the experimental group were significantly lower than those in the control group,with statistically significant differences(P<0.05).Conclusion The application of bundle nursing in DPMAS treatment of patients with liver failure can significantly reduce the incidence of catheter related infection and abnormal hemorrhage,shorten the hospitalization time,and has certain clinical promotion value.