心脏磁共振在扩张型心肌病危险分层及预后评估中的应用进展

扩张型心肌病(dilated cardiomyopathy,DCM)是一类以左心室扩张和左心室收缩功能障碍为主要特征的心脏病,可最终引起心力衰竭、心律失常和猝死,也是目前心脏移植的最主要病因。准确评估DCM患者心脏受累程度,对疾病进行危险分层,识别需密切随访及强化治疗的高危患者尤为重要。心脏磁共振(cardiovascular magnetic resonance,CMR)多模态、多参数成像,常规CMR电影序列能准确评估心脏的形态及功能异常,而基于CMR的组织学与微观结构成像还能为DCM患者的预后提供更多有价值的信息。作者对CMR在DCM的危险分层及预后评估中的应用进展予以综述。

The application of cardiovascular magnetic resonance in risk stratification and prognosis evaluation in dilated cardiomyopathy

Dilated cardiomyopathy(DCM)represents a heterogeneous heart disease characterized by left ventricular dilatation and left ventricular systolic dysfunction,which could eventually result in heart failure,arrhythmia and sudden death and was also the main cause of heart transplantation.It is essential to accurately evaluate the degree of cardiac involvement,stratify disease risk,and identify high-risk individual who require close follow-up and intensive treatment in DCM patients.Cardiovascular magnetic resonance(CMR)is characterized by multi-modal and multi-parameter imaging.Using CMR cine sequences could accurately assess the morphological and functional abnormalities,whereas CMR-based histology and microstructure imaging could also provide more valuable prognosis information for DCM patients.This article will provide the overview of application progress of CMR in the risk stratification and prognosis assessment in DCM patients.