乳腺磁共振背景实质强化的研究进展

乳腺癌作为女性最常见的恶性肿瘤,其发病率及死亡率都较高,且不同分子亚型乳腺癌生物学表现及临床治疗、预后各不相同,寻找乳腺癌针对性和个性化诊断及治疗的影像学标记物是目前研究的热点.乳腺背景实质强化(background parenchymal enhancement,BPE)是正常纤维腺体组织的生理性强化,受多种因素的影...

Research progress of background parenchymal enhancement in breast magnetic resonance imaging

Breast cancer is the most common malignant tumor in women,which has high morbidity and mortality rates,and different molecular subtypes of breast cancer have different biological manifestations and clinical treatment prognosis.Therefore,the search for targeted and personalized imaging markers for diagnosis and treatment of breast cancer is a hot of current research.Background parenchymal enhancement(BPE)on breast magnetic resonance imaging(MRI)is an increasingly studied parameter that reflects the microvasculature of normal breast tissue,is influenced by many factors,and in the diagnosis and treatment prognosis of mammary gland disease has important diagnostic value.BPE has profound implications for women with or at risk of breast cancer,and may assess the curative effect of neoadjuvant chemotherapy of breast cancer.BPE shows promise as an imaging biomarker but many issues need to be addressed before it can be used either to determine screening strategy or the value of risk-reducing interventions.This review analyzes the influence factors of BPE and role in the diagnosis and treatment of breast cancer screening evaluation.