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不同胰十二指肠切除术治疗胰头导管癌的临床效果比较
引用本文:李卓锴,张坤,谭炜,郭敬强,涂朝勇,朱锦德. 不同胰十二指肠切除术治疗胰头导管癌的临床效果比较[J]. 中国现代医生, 2021, 59(17): 49-52
作者姓名:李卓锴  张坤  谭炜  郭敬强  涂朝勇  朱锦德
基金项目:浙江省中医药科技计划项目(2020ZB304)
摘    要:目的 探讨不同胰十二指肠切除术治疗胰头导管癌的临床效果.方法 选取2015年1月至2019年5月于我院诊治的胰头导管癌患者56例作为研究对象进行回顾性研究,分为观察组和对照组,每组各28例,观察组患者采用保留幽门胰十二指肠切除术(Pylorus-preserving pancreaticoduodenectomy,PP...

关 键 词:胰头导管癌  保留幽门胰十二指肠切除术  标准胰十二指肠切除术  临床效果

Comparison of clinical effects of different pancreaticoduodenectomy in the treatment of ductal pancreatic head carcinoma
Abstract:Objective To explore the clinical effects of different pancreaticoduodenectomy in the treatment of ductal pancreatic head carcinoma.Methods A total of 56 patients with ductal pancreatic head carcinoma who were diagnosed and treated in our hospital from January 2015 to May 2019 were selected as the research subjects for a retrospective study.They were divided into an observation group and a control group,with 28 cases in each group.Patients in the observation group were treated with pylorus-preserving pancreaticoduodenectomy (PPPD).Patients in the control group were treated with standard pancreaticoduodenectomy (SPD).The general clinical data,intraoperative and postoperative indicators (intraoperative blood loss,duration of operation,gastric tube indwelling time and length of hospital stay) were compared between the two groups of patients,and the incidence rate of postoperative complications (delayed gastric emptying,intra-abdominal infection,biliary fistula and pancreatic fistula) was investigated.Results There was no statistically significant difference between the two groups in age,gender,history of abdominal surgery,body mass index,total bilirubin,hemoglobin,and albumin(P>0.05);there was no statistically significant difference between the two groups in the indwelling time of the gastric tube and the length of hospital stay(P>0.05);the duration of operation in the observation group was significantly shorter than that in the control group,and the intraoperative blood loss was significantly lower than that in the control group.The differences were statistically significant (P<0.05);the total incidence rate of postoperative complications in the observation group was of 3 cases(10.71%),and the total incidence rate of postoperative complications in the control group was of 4 cases(14.28%),the differences were not statistically significant(P>0.05).Conclusion Compared with the standard pancreaticoduodenectomy,the pylorus-preserving pancreaticoduodenectomy has a shorter duration of operation and less intraoperative blood loss.The safety of both procedures is higher.
Keywords:Ductal pancreatic head carcinoma  Preserving pancreaticoduodenectomy  Standard pancreaticoduodenectomy  Clinical effects
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