谷维素治疗糖尿病周围神经病变疗效观察

目的 观察谷维素治疗糖尿病周围神经病变疗效。方法 回顾性分析我院2019年7月至2020年1月治疗的糖尿病周围神经病变患者152例进行研究,按照治疗方法不同分为两组,每组各76例,其中对照组采取常规治疗措施,研究组在以上基础上实施谷维素治疗,观察两组患者治疗前后VAS评分、踝肱功能评分、生活质量评分、氧化应激水平、MCV、治疗总有效率变化。结果 治疗前两组患者VAS评分、踝肱功能评分、ADL评分比较,差异无统计学意义(P0.05),两组患者治疗前SOD、TAOC水平比较,差异无统计学意义(P0.05),治疗前两组SCV与NCV比较,差异无统计学意义(P0.05);治疗后研究组VAS评分低于对照组,差异有统计学意义(P0.05),研究组踝肱功能评分、ADL评分高于对照组,差异有统计学意义(P0.05),治疗后研究组SOD、TAOC水平高于对照组,差异有统计学意义(P0.05),治疗后研究组SCV及NCV传导速度均快于对照组,差异有统计学意义(P0.05),研究组总有效率为94.74%,高于对照组的80.26%,差异有统计学意义(P0.05)。结论 对于糖尿病周围神经病变患者,可实施谷维素治疗,有效改善患者疼痛情况,并提升患者生活质量,使患者氧化应激水平好转,值得应用。

Observation of the efficacy of oryzanol in patients with diabetic peripheral neuropathy

Objective To observe the efficacy of oryzanol in patients with diabetic peripheral neuropathy.Methods A total of 152 patients with diabetic peripheral neuropathy treated in our hospital from July 2019 to January 2020 were retrospective analyzed and divided into the study group (n=76) and the control group (n=76) according to different treatment methods.The control group was treated with conventional therapy,while the study group was treated with oryzanol on the basis of the control group.Changes VAS score,ankle brachial index and quality of life score,oxidative stress level,MCV and total effective rate were observed before and after treatment in the two groups.Results Before treatment,VAS score,ankle brachial index and ADL score showed no difference between the two groups (P>0.05);oxidative stress level showed no difference between the two groups(P>0.05);and SCV and NCV showed no statistical significance between the two groups(P>0.05).After treatment,VAS score in the study group was lower than that in the control group,and the difference was statistically significant (P<0.05);ankle brachial index and ADL score in the study group were higher than that in the control group,and the difference was statistically significant(P<0.05);oxidative stress level in the study group was higher than that in the control group,and the difference was statistically significant(P<0.05);the conduction velocity of SCV and NCV in the study group was higher than that of the control group,and the difference was statistically significant (P<0.05);the total effective rate in the study group was 94.74%,which was higher than that of 80.26% in the control group,and the difference was statistically significant(P<0.05).Conclusion Oryzanol in the treatment of patients with diabetic peripheral neuropathy can effectively improve their pain,quality of life and oxidative stress level,which is worthy of application.