| 充血性心力衰竭患者血浆脂联素水平测定的临床价值探讨 |
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| 引用本文： | 陈宇凯. 充血性心力衰竭患者血浆脂联素水平测定的临床价值探讨[J]. 中华危重症医学杂志(电子版), 2010, 3(4): 18-20. DOI: 10.3877/cma.j.issn.1674-6880.2010.04.005 |
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| 作者姓名： | 陈宇凯 |
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| 作者单位： | 杭州师范大学医学院附属医院心内科,310015 |
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| 摘 要： | 目的探讨血浆脂联素(APN)水平对于判断充血性心力衰竭患者心功能状态的临床价值。方法采用酶联免疫吸附双抗体夹心法测定57例慢性充血性心力衰竭患者的血浆APN水平,并对其与NYHA心功能分级及左室重构指标、心功能参数如左室后壁厚度(LVPWT)、左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左室射血分数(LVEF)等进行比较和相关性分析。结果慢性心衰患者的血浆APN水平随着NYHA心功能分级升高而升高,并且血浆APN水平与左室重构指标及心功能参数之间存在相关性,即与患者的LVEDD、LVESD呈正相关,与LVEF呈负相关。结论血浆APN水平能较好地反映充血性心力衰竭患者的心功能状态,对于病情评估具有一定的临床价值。
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| 关 键 词： | 充血性心力衰竭 脂联素 心功能分级 心室重构 |
Clinical value of plasma adiponectin in patients with congestive heart failure |
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| Chen Yu-kai. Clinical value of plasma adiponectin in patients with congestive heart failure[J]. Chinese Journal of Critical Care Medicine ( Electronic Editon), 2010, 3(4): 18-20. DOI: 10.3877/cma.j.issn.1674-6880.2010.04.005 |
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| Authors: | Chen Yu-kai |
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| Affiliation: | Chen Yu-kai. Department of Cardiology,the Affiliated Hospital of Hangzhou Normal University Hangzhou 310015,China |
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| Abstract: | Objective To investigate the clinical value of adiponectin (APN) in evaluating the cardiac function for patients with chronic congestive heart failure.Methods The concentrations of plasma APN were measured by Enzyme-linked immunosorbent assay (ELISA) and double antibody sandwich method in 57 patients with chronic congestive heart failure.Doppler echocardiography was performed to determine left ventricular posterior wall thickness (LVPWT),left ventricular end-diastolic diameter (LVEDD),left ventricular end s... |
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| Keywords: | Congestive heart failure Adiponectin Cardiac function classification Ventricular remodeling |
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