肝硬化患者门静脉血栓形成危险因素的Logistic回归分析

目的研究肝硬化患者门静脉血栓（PVT）形成的相关危险因素。方法回顾性分析我院消化内科2007—2008年确诊的肝硬化患者80例,其中19例肝硬化PVT患者作为血栓组,61例肝硬化非血栓患者作为对照组,收集相关临床资料,对可能影响PVT形成的因素进行单因素分析和Logistic回归模型分析。结果Logistic回归模型分析结果显示,血浆D-二聚体、门静脉宽度（MPV）、血小板（PLT）是肝硬化患者PVT形成的独立危险因素（P值分别为0.003、0.012、0.036）。结论肝硬化患者应注意监测血浆D-二聚体、门静脉宽度、血小板等指标,以便早期预防和发现PVT的形成。

Analysis of the risk factors of portal vein thrombosis in liver cirrhosis patients

Objective To research the risk factors of portal vein thrombosis （PVT） in liver cirrhosis patients. Methods Eighty cirrhotic patients with （n=19） or without （n=61） PVT diagnosed during 2007 to 2008 in our Dept. were enrolled. Seventeen common ultrasonographic and serum markers were analyzed. SPSS software was used for statistic analysis. Results Logistic regression model analysis showed that D-dimer,main portal vein width and platelet were the independent risk factors of portal vein thrombosis （PVT） in liver cirrhosis patients. Conclusion D-dimer,main portal vein width and platelet should be monitored in patients with cirrhosis to prevent the occurrence of portal vein thrombosis.