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天芪降糖颗粒制备工艺优选
引用本文:梁海宁,刘效栓,沈涛.天芪降糖颗粒制备工艺优选[J].甘肃中医,2014(10):28-30.
作者姓名:梁海宁  刘效栓  沈涛
作者单位:甘肃省中医院,甘肃 兰州,730050
摘    要:目的:优选天芪降糖颗粒的制备工艺。方法:以成型率、流动性、溶化性为指标,筛选赋形剂、润湿剂品种及配比,优选最佳成型工艺。结果:最佳制粒工艺:天花粉、茯苓粉碎,过80目筛,与流浸膏混合制软材,润湿剂为70%的乙醇,乙醇用量比为20%,CRH65%。结论:颗粒剂工艺合理,简便稳定,可用于大批量生产。

关 键 词:天芪降糖颗粒  制备工艺  无糖颗粒剂

Optimization of Preparation Process of TianQi JiangTang Granules
LIANG Haining,LIU Xiaoshuan,SHEN Tao.Optimization of Preparation Process of TianQi JiangTang Granules[J].Gansu Journal of Traditional Chinese Medicine,2014(10):28-30.
Authors:LIANG Haining  LIU Xiaoshuan  SHEN Tao
Institution:(Gansu Provincial Hospital of Traditional Chinese Medicine, Lartzhou 730050, China)
Abstract:Objective: To optimize preparation technology of TianQi JiangTang granules. Method: The best molding process was optimized by taking the shaping rate, fluidity and dissolubility as the indexes, excipient, the types of wetting agents and proportions were screened. Results:The optimal preparation technology: TianHuaFen (Trichosanthis Radix) and FuLing Poria cocos (Schw.)Wolf.] smashed, 80-mesh screen, mixed with fluid extract to make soft material, wetting agent was 70%ethanol, ethanol volume ratio was 20%and CRH 65%. Conclusion:The preparation of the granule is reasonable, simple and stable, it could be used for mass production.
Keywords:TianQi JiangTang granules  preparation technology  sugar-free granules
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