ICP合并GDM对母儿结局的影响

目的：探讨妊娠期肝内胆汁淤积症（ICP）合并妊娠期糖尿病（GDM）对母儿结局的影响。方法：分析15例ICP合并GDM孕妇和50例单纯ICP孕妇的临床资料。结果：ICP合并GDM组新生儿窒息率、羊水污染率、小于胎龄儿发生率均显著高于ICP组（P〈0.05）。ICP合并GDM组新生儿出生体重较单纯ICP患者轻,分娩孕周较单纯ICP患者小（P〈0.05）。结论：ICP合并GDM对围产儿的影响较大,应加强产前和产时母儿监护,合理评估病情,必要时促进胎肺成熟,适时终止妊娠,以改善围生儿不良结局。

EFFECTS OF INTRAHEPATIC CHOLESTASIS OF PREGNANCY COMBINED GESTATIONAL DIABETES MELLITUS ON MATERNAL AND FETAL OUTCOMES

Objective：To investigate the effects ofintrahepatic cholestasis of pregnancy（ICP） combined gestational diabetes mellitus（GDM） on maternal and fetal outcomes.Methods：The clinical data of 15 cases ICP combined GDM and 50 cases ICP pregnant women were analyzed.Results：The neonatal asphyxia rate,incidence of amniotic fl uid contamination and incidence of small for gestationel age infants of ICP combined GDM pregnant women were all obviously higher than that of ICP pregnant women（P 0.05）.The newborn birth weight of ICP combined GDM group was signifi cantly lower,and the termination time of pregnancy of ICP combined GDM group was signif icantly earlier than that of ICP group（P0.05）.Conclusions：ICP combined GDM has great inf luence on perinatal infant.We should strengthen antenatal and intrapartum maternal and perinatal care,evaluate the disease reasonably,timely termination of pregnancy,so to improve the adverse outcome of perinatal infant.