| 血浆Hcy水平与绝经后骨质疏松的相关性研究 |
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| 引用本文： | 姜惠.血浆Hcy水平与绝经后骨质疏松的相关性研究[J].承德医学院学报,2012,29(3):253-255. |
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| 作者姓名： | 姜惠 |
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| 作者单位： | 姜惠 (镇江市第一人民医院内分泌科,江苏镇江,212000) ； |
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| 摘 要： | 目的:探讨血浆同型半胱氨酸(Hcy)水平对绝经后骨质疏松的影响。方法:调查200名绝经后妇女,采用双能X线吸收法(DXA)测量骨密度,采用Hcy荧光定量检测试剂盒检测血浆Hcy水平。结果:骨质疏松组血浆Hcy水平明显高于非骨质疏松组,差异具有统计学意义(P<0.05);骨质疏松组血浆Hcy水平与骨密度呈显著负相关(r=-0.16,P<0.05),相对危险度OR为9.214(95%CI=3.28-29.92)。结论:血浆Hcy水平升高是绝经后骨质疏松的独立危险因素。
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| 关 键 词： | 同型半胱氨酸 绝经 骨质疏松 |
STUDY ON THE RELATIONSHIP BETWEEN PLASMA HOMOCYSTEINE LEVEL AND POSTMENOPAUSALOSTEOPOROSIS |
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| JIANG Hui.STUDY ON THE RELATIONSHIP BETWEEN PLASMA HOMOCYSTEINE LEVEL AND POSTMENOPAUSALOSTEOPOROSIS[J].Journal of Chengde Medical College,2012,29(3):253-255. |
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| Authors: | JIANG Hui |
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| Institution: | JIANG Hui(Department of Endocrinology,the First People’s Hospital of Zhenjiang,Jiangsu Zhenjiang 212000,China) |
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| Abstract: | Objective:To investigate the relationship between postmenopausalosteoporosis and plasma homocysteine(Hcy) level.Methods:200 postmenopausal women were inquired in this study.The bone mineral density(BMD) of the 200 women were detected by DXA,plasma Hcy level were detected by high-performance liquid chromatography-fluorescence detection(HPLC-FD).Results:The plasma level of women in osteoporosis group was obviously higher than that of non-osteoporosis group(P< 0.05).In osteoporosis group,the plasma level had obvious negative correlation with osteoporosis (r=-0.16,P< 0.05),the relative risk OR was 9.214(95%CI=3.28-29.92).Conclusions:Hyperhomocysteinemia is the independent risk factor for postmenopausalosteoporosis. |
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| Keywords: | Homocysteine Menopause Osteoporosis |
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