| 高尿酸血症与糖代谢异常的关系 |
| |
| 引用本文： | 李明珍,聂秀玲,孙丽荣. 高尿酸血症与糖代谢异常的关系[J]. 国际内分泌代谢杂志, 2016, 0(4): 217-219. DOI: 10.3760/cma.j.issn.1673-4157.2016.04.01 |
| |
| 作者姓名： | 李明珍 聂秀玲 孙丽荣 |
| |
| 作者单位： | 300070 天津医科大学代谢病医院糖尿病痛风科,天津医科大学代谢病医院内分泌研究所,卫生部激素与发育重点实验室,天津市代谢性疾病重点实验室 |
| |
| 摘 要： | 生活方式及饮食结构的显著改变,使得高尿酸血症患病率明显增加.尿酸在体内作用相当复杂,目前的临床和基础研究结果提示,高尿酸可通过多种信号通路影响β细胞及其功能、参与胰岛素抵抗的发生,与糖代谢异常密切相关,并可独立预测2型糖尿病的发生.关注二者之间的关系将有益于临床诊治.
|
| 关 键 词： | 高尿酸血症 糖代谢 胰岛素抵抗 β细胞 |
Relationship between hyperuricemia and abnormalities of glucose metabolism |
| |
| Abstract: | The prevalence of hyperuricemia has been increasing dramatically,with the modem changing of diet and lifestyle.The role of uric acid in the body is very complex and mixed.Up to now,studies from clinic and rodents show that high uric acid is strongly correlated with impaired glucose metabolism,and also is an independent predictor for type 2 diabetes.Hyperuricemia could possibly affect β cells in pancreas and involve in insulin resistance through many signal pathways.It will be good for clinical management to keep an eye on relating researches. |
| |
| Keywords: | Hyperuricemia Glucose metabolism Insulin resistance β cells |
| 本文献已被 万方数据 等数据库收录！ |
|
